Scientific paradigms: The importance of stem-cell banking
Kohima, February 19
Life Cell is India’s first and largest stem cell bank which was Established in 2004, and is India’s first and largest stem cell bank enjoying the trust of 1,00,000 parents who have banked their children’s stem cells with the company.
With state-of-the-art laboratories at Chennai and Gurgaon and a network spread over 100 service centers in the country & footprints in GCC countries, Life Cell is also the most recommended stem cell bank by gynecologists.The company is also the most accredited stem cell bank with certifications from national and international organization, this was stated by Brig.(DR Paramjitsingh while addressing at Workshop on scientific awareness stem cell banking held at Hotel ACACIA at Dimapur on 11th of February 2015th with resources person Brig.(DR) Paramjit Singh DHOT from Life cell international PVT Ltd Gurgaon to create awareness on the stem cell banking from which people can benefit by way of treatment of more than 80 medical conditions which was attended by senior doctors from Kohima and Diampur.
Brig. (Dr. Paramjitsingh DHO inform that Life Cell is also the only player in the industry providing comprehensive stem cell solutions including menstrual stem cell banking, R&D and point-of-care stem cell therapy for orthopedic, vascular and cardiovascular specialties He added that Stem cells have the ability to divide for indefinite periods in culture and to give rise to specialized cells and are the best described in the context of normal human development. Human development begins when a sperm fertilizes an egg and creates a single cell that has the potential to form an entire organism and this fertilized is tot potent, meaning that its potential is total. In the first hours after fertilization, this cell divides into identical tot potent cells which means that either one of these cells, if placed into a woman’s uterus, has the potential to develop into a foetus.
Paramjit Singh mentioned that Cells capable of giving rise to most tissues of an organism are called pluripotent and comprise the inner cell mass cells in an embryo. The pluripotent cells undergo further specialization into stem cells that are committed to give rise to cells that have a particular function.
The first transplantation of Umbilical Cord Blood was successfully performed in October 1988 by Gluck man et al to treat a boy with Fanconi’s anaemia and he is alive, well and completely cured of the hematological and life threatening manifestation of his disease more than 25 years after the procedure. The donor, the Gluck man et al was his new born sister was a perfect HLA match for her brother. The medical fraternity is excited by the current state of knowledge and the immense potential in the exponential development in this field.
The major limitations of using HLA- matched related sibling donors in HSCT emphasize on the facts that only 30% to 40% of recipients have a HLA- matched related family donor hence the search for an alternative source of HSC. New born Screening (NBS) is a simple test taken at birth to enable early detection of condition in babies.
The conditions screened for are individually rare but collectively more common. -1 in 300 are diagnosed in US based on population screening for 29 conditions. The purpose of new born screening is to enable early detection of pre-symptomatic babies, to enable early treatment, to improve health, to reduce anxiety caused by uncertainty over symptoms before clinical diagnosis is made. NBS is a public health success story. It is mandated by almost all developed countries as it saves lives, prevents disability, and in fact saves money.
The widespread implementation of NBS in the US led it to its recognition as the ‘Ten Great Public Health Achievements’ in the US, between 2001 – 2010 (CDC, May 2011).